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Cat No. | Product Name | Synonyms | Targets |
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T39685 | PCSK9 degrader 1 | ||
PCSK9 degrader 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) degrader. PCSK9 degrader 1 does not affect PCSK9 function. | |||
T13813 | PCSK9 ligand 1 | Others | |
PCSK9 ligand 1 is a small molecule ligand for proprotein convertase substilisin-like/kexin type 9 (PCSK9) and shows high affinity to PCSK9(Ki of 107 nM). | |||
T39528 | PCSK9-IN-2 | PCSK9-IN-2 | |
PCSK9-IN-2 is a newly developed small molecule that effectively inhibits the protein-protein interaction (PPI) between PCSK9 and LDLR. It has been found to have a potent inhibitory activity with an IC50 value of 7.57 μM. | |||
T39122 | Inclisiran | ALN-PCSsc | |
Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) compound that effectively suppresses PCSK-9 transcription. It proves promising in the investigation of hyperlipidemia and cardiovascular disease (... | |||
T76974 | Tafolecimab | ||
Tafolecimab (IBI-306), a human IgG2 monoclonal antibody, specifically targets and binds to PCSK-9, thus inhibiting PCSK-9-mediated endocytosis of the LDL receptor. This action enhances the clearance of LDL-C, resulting i... | |||
T74248 | AS-Inclisiran | ||
Inclisiran (ALN-PCSsc), a double-stranded small interfering RNA (siRNA) compound, serves as the antisense of itself and targets PCSK-9 transcription inhibition. It is employed in the study of hyperlipidemia and cardiovas... | |||
T74876 | GalNAc unconjugated/naked Inclisiran | ||
Inclisiran (unconjugated/naked) is a double-stranded small interfering RNA (siRNA) that lacks GalNAc conjugation. This compound selectively inhibits the transcription of PCSK-9, making it applicable in the research of hy... | |||
T74249 | AS(3n-2)-Inclisiran | ||
Inclisiran AS(3n-2), an antisense variant of Inclisiran, features a 2 bp spacer followed by 3 random N sites. Inclisiran itself is a double-stranded small interfering RNA (siRNA) molecule designed to suppress PCSK-9 tran... |
Cat No. | Product Name | Species | Expression System |
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TMPK-00483 | PCSK9 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1.The first two PCSK9 inhibitors, alirocumab and evolocumab, were approved as once every two week injec... | |||
TMPJ-00443 | PCSK9 Protein, Macaca nemestrina, Recombinant (His) | Macaca nemestrina | Human Cells |
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in ... | |||
TMPJ-00369 | PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated | Human | Human Cells |
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processi... | |||
TMPJ-00368 | PCSK9 Protein, Human, Recombinant (Avi), Biotinylated | Human | Human Cells |
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processi... | |||
TMPJ-00865 | VEGF121 Protein, Human, Recombinant (His) | Human | Human Cells |
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD... | |||
TMPH-00005 | YAP1 Protein, Human, Recombinant (Isoform 9, His) | Human | Yeast |
YAP1 Protein, Human, Recombinant (Isoform 9, His) is expressed in Yeast with C-terminal 6xHis tag. The predicted molecular weight is 56.4 kDa. Accession number: P46937-9 | |||
TMPY-03698 | VEGF121b Protein, Human, Recombinant | Human | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPK-00825 | VEGF121 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPY-05268 | Neurofascin Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 |
NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM famil... | |||
TMPK-00826 | VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... |